MCQ ON PHARMACEUTICAL INORGANIC CHEMISTRY
Which of the following is used as a respiratory stimulant? A) Sodium chloride B) Ammonium carbonate ✅ C) Calcium gluconate D) Sodium fluoride What is the mechanism of action of Ammonium carbonate? A) Central depression B) Reflux stimulation of respiratory tract ✅ C) Enzyme inhibition D) Protein synthesis Sodium fluoride is used as: A) Laxative […]
LIMIT TEST FOR ARSENIC
The pharmacopoeial limit test of arsenic is a qualitative comparative test bsed on Gutzeit test in which arsenic impurity present in the sample is reduced to arsine gas and then it is passed through on mercuric chloride paper as a yellow to brown stain, Which is compared against prepared standard stain as prescribe by Pharmacopoiea.If […]
History of Medicinal Chemistry.
Medicinal chemistry is an interdisciplinary subject of science which combines organic chemistry, pharmacology, biochemistry, and molecular biology to design, synthesize, and able to develop pharmaceutical compounds. The history of medicinal chemistry arises from ancient herbal remedies to modern rational drug design,It reflects the mankind’s constant attempt to understanding and treat illnesses by chemical treatments. 1.Ancient […]
Radioactivity
What is Radio activity? In 1 March, 1896 Henry Bacquerel (French) was accidentally found that certain substances (Urnanium containing minerals) spontaneously emitting the invisible light radiation and effect on photographic plate. This activity of substance was termed as radioactivity. Radioactivity- The phenomenon of spontaneous emission of certain invisible radiation by some elements are called radioactivity. […]
Sources of Impurities.
Impurities are unwanted substances (foreign substances) that are present in chemical substances and drugs, which may harm their quality, safety, and effectiveness. They may come from different sources like during their preparation,storing , or handling . In inorganic pharmaceuticals these impurities are often as heavy metals, extra ions, or intermediate products. The different sources of […]
Assay of Sodium Chloride
Assay – As per I.P Assay of Sodium Chloride is performed by Modified Volhard’s Method:(I.P.1985)An accurately specified amount of sample is weighed and dissolved in water, Than it is treated with a known excess of N/10 silver nitrate, concentrated nitric acid, and nitrobenzene. Further the mixture solution is titrated with N/10 ammonium thiocyanate using ferric […]
Assay of Chlorinated lime or Bleaching Powder.
To determine the amount of “available chlorine” in chlorinated lime (bleaching powder), the Indian Pharmacopoeia (IP) recommends using an iodometric titration method. Chlorinated lime must have at least 30.0% w/w of accessible chlorine, according IP requirements. Principle The assay is based on the principle that the “available chlorine” present in chlorinated lime. Chlorinated lime release […]
Assay of Hydrogen Peroxide
This method is official in major pharmacopoeias and is widely used for its accuracy and simplicity in pharmaceutical analysis. The assay of hydrogen peroxide (H2O2) is typically performed using redox titration with a standardized solution of potassium permanganate (KMnO4) in an acidic medium. Principle– The principle behind this method is the oxidation-reduction reaction between the […]
Pharmacopoeia
What is a Pharmacopoeia? A pharmacopoeia is a legal and scientific reference book that sets the standards for the identity, purity, strength, and quality of pharmaceutical substances and medicinal preparations. It contains a collection of monographs, which are detailed descriptions of individual drugs, and general chapters that outline the official tests and procedures for their […]
Lisdexamfetamine: A Helpful Medicine for ADHD and Binge Eating Disorder( BED)
Lisdexamfetamine is a medicine that helps people with two main problems: ADHD (Attention Deficit Hyperactivity Disorder) and binge eating disorder( BED). It is sold under brand names like Vyvanse and Elvanse. How It Works ? Lisdexamfetamine is a “prodrug,” which means it only starts working after your body changes it into another substance called dextroamphetamine. […]